An efficient method for zinc mediated reduction of norbornyl α- diketones in [bmim][BF4]:H2O

نویسنده

  • Faiz Ahmed Khan
چکیده

Efficient reduction of monoand disubstituted norbornyl α-diketones with zinc in [bmimBF4]:[H2O] to afford the corresponding acyloins in excellent yields and diastereoselectivities is described. In case of the monosubstituted norbornyl α-diketones, very high regioselectivities ranging from 90:10 to 100:0, in favor of diastereomer possessing endohydroxyl diagonal to endo-substituent were observed.

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تاریخ انتشار 2009